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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c32095b0ab568d2405ddba3e441940d80a2a7fc969e0df090b70f096bfe5b057' 
  AND token = 'CWNspi7faltmHr0TTtTCFUyiOM/7DP9ZD9Z8rEjxPAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}