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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5df541e1f1e043f1259e1a3c7169a6b55a7f3639c2c3481adad6247089d1bd81' 
  AND token = '9XdNYqm4NN/jawvcq61evQpRIOwlAcf12GRqrjtOCkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}