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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42028efb41c61ed98385c006693d502d282fb18c7610e8037624dd268c1720d' 
  AND token = 'vsM6ouqVfGjWzOg1ByK0avhkhv7nnWfbueZoWj7OQ+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}