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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6018b19b6f59de01cfa6bb4e8814de612513240cd333e898814a1a5a3ad26c6f' 
  AND token = 'ddpJJXeBTvk30kwluEnIIzZA2Vf28xaJxnQ0CS6HRPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}