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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '909a2348380675bc49948b22bfc568349f3ae5144db437999b0646bbb7c33253' 
  AND token = 'WETEn3iiFw/Er6bdl+geDB35W9UEn9rzpvLdH8SA2uI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}