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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3285afef39ee13944e522347b940f21c884cd1a6408b3fee9036206fb7226fc5' 
  AND token = 'ZfIqoQEEARUEG5kQi/fJwvxHdCLKd+LMDr9CgfmNe7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}