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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd9fc8503feece2286e32b0d88250f5a6334c11a1ed6d91b5c45b48e1336a0d7' 
  AND token = 'AqwMmnxnHr/OtjHDwXZ+IWzb53CNtVx7+OpIwEIk9jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}