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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3877e69c8e905963a5595a8c84c3f62ef1429322863002de6412b9cded52c4f9' 
  AND token = 'doINUiHe9rTKY59LZtOGNUBHJ/Jimic90gTIFICEdw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}