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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80a17547d37706d5926ab13be2b0c950d7db2ff0af97e5499db5c51b8305f8ec' 
  AND token = 'nmCCFQ5LaQFFKZFdFeqdcEf2Apf0FTrfxsSjlRME8C8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}