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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c72792ab05a313db1aa0170825708b7317f998801b989b1cfda279693c04c61' 
  AND token = 'ZhmkknZ5rrBGH0ZipJuimxLFDW+E8VkfLnkO4qlF3Ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}