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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4752315f8f8db454417a5e3cb67fa8eb0f8d8d22534ff3316de148878c01abf' 
  AND token = 'HEo6LW041hbu5PSx/XeDwoEL1W9OKHRJAs5diIzZjOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}