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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac014640ce12b065e0535dfa68751ad081e170cb5d0ae6a563538f4cf9ec3aa' 
  AND token = 'D05Ky0acQENgAJ3KH9Pb9Ox4tWE+REdIbwckAq2TZzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}