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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa8415242cdae9b4c857e885d6d9efa6ce10b9a43b6b3453480559193a09a379' 
  AND token = 'gHtRHBZOUKtl2/zvu8FooXrxyxLRhm2Ccoe8RODAoFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}