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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f4697e571169a9e4de7aa8ac422e3cfc67e3b5ffca8ef306fac9aaabdadf354' 
  AND token = '7pFRRSXqPCY1Fpwl8YM6cA1QMPH7xIxnVSe/Ak+y/EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}