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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc8e841b22f1ec701ccb89c9d8e45dd0398088d0109ce0e2154a2e587d5e3b21' 
  AND token = 'WFucVEHaDK/auYUo3m5Voba3ml2ofwFLE1F82xXKoE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}