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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75bea2e7f2fa3899239e14ee8280ac23741278d01bf69d2d74b3245bd882b31f' 
  AND token = 'AJTpHpqpu3rkAyy5YaMSCMf7vLts7N4Momg6dEGoNmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}