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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68bdb6c8e704881d4491c8e5a5239bd39d544bcc2a3970db400786d4f328e946' 
  AND token = 'U1LIltE78HH0tK7ou3NsWNUhSGLrBQNibtyjHI27sAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}