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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d7fed66dd3530ba928847d5aa47f7df7f0a2fd2f459cf8361cb1dc66a19186e' 
  AND token = 'n4azG9zRq1tPmw1ktCdCuPW0qlBdqwmKFf73mVqrrTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}