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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad01b04611ebaf7bb34b2ef503d1a357270a4f3638bcdf1257c82c3e96eadc6f' 
  AND token = 'tlk4vSg4nAgmcf2DRqnCpSuK1A/qQTGExY36m0koM8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}