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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '067341b56a1355bd07ce003438a6432f504d51c984c2e9458bbd08fe9eac27da' 
  AND token = 'CPu+ry0rZYTO5Ytj/ppM+M8sQCyFx8Hpt6jITTiN6zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}