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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b99b9cde713d6600752147911cb60d1d391c2d5d577cb93a434f0c572e86a4c' 
  AND token = 'iCh63IuZym6ZrsrVJTJ+/HneSgAB/REsPtoi8lOb6fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}