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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cffa9d18340faf8c703985cd6b1ceead05741cad7a09ac221edb9c65d77d05e6' 
  AND token = 'R3MeAqt8J6C21flhxdCe3MoqeNe8hsD9a739cxfuJ/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}