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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd617c35583406195db44c9386d1b9c9c273532b3156f53001a5b0b1541f6ec3a' 
  AND token = 'SedhrkPe0ZhqIDPK3rEMUsbeQgAtPS65LX6p0UDqIWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}