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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e018b1f66e47323ed836bc2a840f6aa57a29ebfcb8b44212d05afb4f0050c81b' 
  AND token = 'NNwf7DS/0Yg6ME5dXfaQRebT5RarayroNf+SUSj2Ot4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}