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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a27a7b1ed983d099abca2d3bb1eaa4e0c7e0bd51c270708f63cb84d97813d401' 
  AND token = 'AUZnYev1DjY7ApphvSAzzH76SPvuKsQGnoi9nt7SrZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}