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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '661de4e7b439a95d097685d4ca467dff3bf86934659c914baaa8d42911da70bb' 
  AND token = 'brfi6EIHE4X+gx9rTxrZs2OMBx0WZtW/XwJobz5YzPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}