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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cef9455851c61d6690322f62ac9315fa16c240e1c698e8e90d5a48d0c790555' 
  AND token = 'u0IWRNWsMSaEHir8sgeSzf/L927rPBJfxz8e7CRgiv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}