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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '423edf2e4d4baf48ad71fe7c24da3d3742d341c46fd20c1e75ac6fd035f1e2a4' 
  AND token = 'p8JvDFGDaw1FveORpA9sR9sN3Hz1G9jbtR5gblnw7Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}