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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43c35996ca100446d62f78560efe325cee15f125c31ba499b2e2ea0c2aee9cb' 
  AND token = 'oz/6SqpGrnEfrjmqJ5Wx42VgIKDQ5+4knNh3UGvpzJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}