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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666a9bdc53ea218d4682a2476c7676910876ce2f3e28c2f1ed687ddc9d1caf13' 
  AND token = 'oD2zsE3gwlNdxoWszCRfDBiHpRvRvGS7ypCAv9PC414=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}