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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c478572465c418c4851d8a1437b315fb8fab9250df9a8d9c6b4b2dc4c6c765b9' 
  AND token = 'Id01VjUgjuH9LaXb6WiYqz/aZjaNtiDQttZm/KftDpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}