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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6da61c95b6b12bbb2634d7dabaa81952686f9fc512b98a0d3501cda199c4f459' 
  AND token = 'R3hSf5WC1oUDBzh587OEcf0pCfwEimHOyvh85kV4XnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}