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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '097250b8909e0b805f4482da4d6ba03c3eaf76b40a3a4eed3fdae02af49ceec1' 
  AND token = 'r6vsiKPC5/C9Iy9kckmDwQr5J0kaRRnv1wO+tMh1WVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}