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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '322e46c469d1b08a0dd055cc100619a4aa53390110e994238729ed7c57295608' 
  AND token = 'KR7uUr190TMy0RCrXOsDhi7zZOcp/gQfMibnMQ/thCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}