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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1846d02e235f0bbc1d4dcb27142a1579750462264346bcc8d1ba14c11858378' 
  AND token = 'Qhk2y8OF9RgPceIS86cV4biMts/e34aD65097i4RjnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}