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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf385b6d5412c70d7021a6a496759bcbb65a953585f69827e35671e4e9248829' 
  AND token = 'a4rkDiEK+BTdDn5j28EUZZoCBbouvgW5TPP0rb5kZo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}