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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f49c6dda3c4f63c39cc589ee26028e6cdeda63af8ae96c180d5019581ddd5213' 
  AND token = 'V5/Qe62HTccrRKpV4gIEa7B3pjC2IQAoOpLLenh4eD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}