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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9010a2d7336f1702c4578205f6e63675dfc1f1ef07906b5f33d72e8f1799381' 
  AND token = 'czdUPeuWgIpodqhSIbuWTT8M0PnZr3lgCdOf+18jk8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}