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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5cdfcadcbe9881fd7c01bc65a48b53c0b26bccfcc6f41620dbc113be8b5a549' 
  AND token = 'srQcr01EPojNVCn6FNyg0nTAg7X6x29KAStpDU/FT+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}