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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fe7aef3ca690907aa51a236600c72571d952584c143e9c65c73cc7c832dc181' 
  AND token = 'VhwH0gWa8ZcT5Je5NLJdecXPW61Hs4hvMFwt1zC7Gvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}