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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e9b91811c46ce0e2692e11d300b1197694c2b4a9f121ffae644d0c4a3b1fb8' 
  AND token = 't/cf8TOSHfEm1/QimChOGIniHZkpv7ca1tNWQq9fMWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}