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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0649e7d5aa38bc9c401a5567476eecc59b245b405a5e5bfda0dfe5fb8d9bcd2' 
  AND token = 'K+75e0wLWp/bzGXuG/ond98m2OPCojIVdKNruhJrjOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}