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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb79d021579a5fe30b605ad75e6af29f99d7b948ddef1b7789651605d3da28da' 
  AND token = 'AEXXz6O5fTE1jUvnoX+v3UPyO7H7daAvUUwxp04Gank=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}