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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66dbd27f01146297d5a15944d4044dd7b8aa78f91925dc66bd347ff2a234ce13' 
  AND token = 'UT+BOiCMc3e+fLGKHfv7tMPN1yiNSf6uxxpHeotdBiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}