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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79adeb37edd0b1655942f16e2d8855e58547da3b51b0e3a3ee7e3166bc962cfd' 
  AND token = 'yEKU4K+61VNXXGYFDCLl8yX/iLNj82md7QfMV25vXEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}