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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eab56a30115aceb515bfdbbe4ce24236d3d41021b2f5db63d4410d9ea14cb23' 
  AND token = 'dtAPCQHorZ6NOODgmQiA1EPqLzw80tCBAKJ1YoDnFMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}