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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28423ab2252a7fb6b62d9a37eaa9b3bb0db1415e635bb42f0d9579336dcfa365' 
  AND token = 'u5spocPUbfcESvZeKw8LhZxj4oKDooUxZvPNA4ZR1oE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}