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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6f9c3c337faa982d2eb600d00e7dee06ff2b16cf77d7ad4578fde4191aeb166' 
  AND token = 'F5lk7XjdtVn8UOKvkLi23Hhi4XNA8t9DXkpyhuQkSVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}