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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b6c5e04940de6de0b3fc30b708a4b16747dc62bb1911379c6b0097a22073d2' 
  AND token = '7ex0Bg9ckjZjrRblTAWeuR61PmQbYtK4VN0+rKKQRg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}