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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f59d76bcf2d6c5b64d4d77edddd252b3cc6739284ecbf7948717267e73c65ace' 
  AND token = '6E9rB/8Aoq+o0VGof3hrhC8PeJAri1Hp4ejijgNPO4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}